Blood-brain barrier dysfunction in brain diseases: Clinical experience
نویسندگان
چکیده
منابع مشابه
P 61: MicroRNA as a Therapeutic Tool to Prevent Blood Brain Barrier Dysfunction in Neuroinflammation
Endothelial cells present in brain are unique and differ from other peripheral tissues in a number of ways, which ensures specific brain endothelial barrier properties. Endothelial dysfunction is the earliest event in the initiation of vascular damage caused by inflammation. Various microRNAs (miRNA) have been discovered in different cellular components of the blood bran barrier (BBB). miRNAs a...
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Disorders of the developing brain represent a major health problem. The neurological manifestations of brain lesions can range from severe clinical deficits to more subtle neurological signs or behavioral problems and learning disabilities, which often become evident many years after the initial damage. These long-term sequelae are due at least in part to central nervous system immaturity at th...
متن کاملThe blood-brain barrier in neuroinflammatory diseases.
I. The blood-brain barrier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 A. Morphology and function. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 B. Mechanisms of transport of compounds across the blood-brain barrier . . . . ....
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لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملPeripheral markers of brain damage and blood-brain barrier dysfunction.
PURPOSE Occurrence of brain damage is frequently associated with abnormal blood-brain barrier (BBB) function. Two brain-specific proteins, S100beta and neuron-specific enolase (NSE) are released systemically in a variety of neurological diseases, but S100beta levels sometimes rise in the absence of neuronal damage, suggesting that S100beta is a marker of BBB rather than neuronal damage. METHO...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2012
ISSN: 0013-9580
DOI: 10.1111/j.1528-1167.2012.03697.x